ELK Biotechnology B4GT6 rabbit pAb
B4GT6 rabbit pAb는 인간, 생쥐, 랫드에 반응하는 폴리클로날 항체로 WB와 ELISA에 적합합니다. 골지체 단백질 표적에 특이하며, β1,4-갈락토실전이효소 관련 연구에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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B4GT6 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | B4GT6 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 42 kD |
| GeneID (Human) | 9331 |
| Human Swiss-Prot No. | Q9UBX8 |
| Cellular Localization | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Trans cisternae of Golgi stack. |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars such as GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus, which remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1/2, beta4GalT3/4, beta4GalT5/6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis. [provided by RefSeq]
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