Thermo Fisher Scientific USP11 Polyclonal Antibody
USP11 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 266–311 of Human USP11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719307 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920-amino-acid deubiquitinating enzyme that participates in the ubiquitin pathway. Localized to the nucleus, USP11 associates with Ran BP-M (Ran binding protein M) and the tumor suppressor BRCA2. Through these interactions, USP11 inhibits or removes ubiquitin residues from these proteins. USP11 is implicated in several X-linked retinal diseases and may play a role in tumor suppression due to its ability to deubiquitinate BRCA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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