Thermo Fisher Scientific ABCB8 Polyclonal Antibody
인간 ABCB8 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 기반 완충액에 보관. 미토콘드리아 내막 단백질 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ABCB8. Recombinant protein control fragment (Product #RP-91129) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637534 |
Product Specific Information
Immunogen sequence:
LFRVGIRGGP FPGRLLPPLR FQTFSAVRYS DGYRSSSLLR AVAHLRSQLW AHLPRAPLAP RWSPSAWCWV GGALLGPMVL SKHPHLCLVA LCEAEEAPPA SSTPHVVGSR FNWKLFWQFL
- Highest antigen sequence identity to orthologs:
- Mouse: 68%
- Rat: 65%
Target Information
This nuclear gene encodes a multi-pass membrane protein targeted to the mitochondrial inner membrane. The encoded protein functions as an ATP-dependent transporter, potentially mediating the passage of organic and inorganic molecules out of mitochondria.
Loss of function in the related mouse gene disrupts iron homeostasis between mitochondria and cytosol.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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