Thermo Fisher Scientific LILRA4 Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1:1,000–1:10,000

Product Specifications

Product Specific Information

• Recommended positive controls: THP-1
• Predicted reactivity: Chimpanzee (96%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

ILT7 is a pDC-specific IgG-like transcript and a member of the leukocyte immunoglobulin-like receptor gene family. This receptor, in complex with FcER1a, transduces ITAM-mediated signals that negatively modulate type I IFN production by pDC. ILT7 is thus a potential target to regulate Type I IFN production by pDC, which play a major role during viral infection, autoimmune diseases, and anti-cancer immunity. Additionally, ILT7, along with CD123 and BDCA-2, can be used to identify or classify subsets of pDC along with TLR expression and TLR-mediated immune responses.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.