Thermo Fisher Scientific ERK1/ERK2 Monoclonal Antibody (3A1)
ERK1/ERK2 단백질 검출용 Mouse Monoclonal Antibody (Clone 3A1). Western blot 및 ELISA에 사용 가능. HepG2 세포를 양성 대조군으로 권장. 세포 분화 및 신호전달 연구에 적합. -20°C 보관, 동결/해동 반복 피할 것.
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Thermo Fisher Scientific ERK1/ERK2 Monoclonal Antibody (3A1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A1 |
| Immunogen | His-tagged recombinant human ERK1 protein purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1958816 |
Product Specific Information
A suggested positive control for this product is HepG2 cells.
Target Information
ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
They are activated by various stimuli including growth factors, cytokines, virus infection, and ligands for G protein-coupled receptors.
Upon activation through the Ras-Raf-MEK-ERK signaling cascade, ERKs phosphorylate cytoplasmic targets or migrate to the nucleus to activate transcription factors such as c-Fos and Elk-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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