Thermo Fisher Scientific JMJD1B Polyclonal Antibody
JMJD1B 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 저장. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human JMJD1B. Recombinant protein control fragment (Product #RP-91620). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642852 |
Product Specific Information
Immunogen sequence:
GEVDSNGSDG GEASRGPWKG GNASGEPGLD QRAKQPPSTF VPQINRNIRF ATYTKENGRT LVVQDEPVGG DTPASFTPYS TATGQTPLAP EVGGAENKEA GKTLEQVGQG IVASAAVVTT ASSTPNTVRI SDTGLAAGTV PE
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 90%
Target Information
Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in the histone code.
Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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