Thermo Fisher Scientific KAT II Polyclonal Antibody
KAT II 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ELISA, Immunoprecipitation에 적합. Mouse 반응성, Affinity chromatography로 정제, 고농도 액상 형태. 연구용으로만 사용.
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Thermo Fisher Scientific KAT II Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KAT II affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the N terminus of mouse KAT II. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl, 30% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
A BLAST analysis suggests cross-reactivity with human, rat, and mouse based on 100% sequence homology. Cross-reactivity with KAT II from other sources has not been determined.
Target Information
This gene encodes a protein highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities:
- Transamination of alpha-aminoadipic acid, a final step in the saccharopine pathway (major pathway for L-lysine catabolism)
- Transamination of kynurenine to produce kynurenine acid, precursor of kynurenic acid with neuroprotective properties
Two alternative transcripts encoding the same isoform have been identified; additional alternative transcripts and isoforms may exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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