Thermo Fisher Scientific DCP1A Polyclonal Antibody
Thermo Fisher Scientific의 DCP1A Polyclonal Antibody는 인간 DCP1A 단백질(475-525 잔기 영역)을 면역원으로 제작된 Rabbit IgG 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 액상 형태로 4°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 475 and 525 of human DCP1 Decapping Enzyme Homolog A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Signal transduction of TGF-beta superfamily members is regulated by Smad proteins. Smads relay signals from the cell membrane to the nucleus to influence gene transcription. Smad4 plays a central role in TGF-beta-induced transcriptional activation by associating with phosphorylated receptor-associated Smads. SMIF (Smad4-interacting protein) and Smad4 form complexes with TGF-beta and BMP4, promoting nuclear translocation. The interaction between SMIF and Smad4 occurs via the EVH1/WH1 domain on SMIF and a proline-rich activation domain on Smad4. Deletion of the Smad4-interacting domain in SMIF prevents TGF-beta-induced nuclear translocation. The human SMIF gene is ubiquitously expressed and encodes a protein of approximately 70 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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