Thermo Fisher Scientific QPRT Monoclonal Antibody (OTI2H4), TrueMAB
인간 QPRT 단백질을 인식하는 Mouse IgG1 단일클론 항체로서 WB, ICC/IF, Flow Cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 저장용액. 신경퇴행성 질환 연구용 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H4 |
| Immunogen | Full length human recombinant protein of human QPRT produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
QPRT gene encodes a key enzyme in the catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway.
Quinolinate acts as a potent endogenous excitotoxin to neurons.
Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer’s disease, and Huntington’s disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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