Thermo Fisher Scientific KaryoStat HD Assay
고해상도 전장유전체 분석으로 염색체 이상을 정확히 검출. >99% 민감도로 25–50 kb 복제수 변화를 탐지. SNP 기반으로 모자이크 및 AOH 분석 가능. 배열, 시약, 분석 소프트웨어 포함. 줄기세포 연구용으로 빠르고 경제적인 솔루션 제공.
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Applied Biosystems™ KaryoStat™ HD Assay
The KaryoStat HD Assay offers genotyping (sample ID) plus high-resolution whole-genome coverage for accurate detection of chromosomal abnormalities.
The assay provides greater than 99% sensitivity and can reliably detect 25–50 kb copy number changes across the genome with high specificity using single-nucleotide polymorphism (SNP) allelic corroboration.
These high-density SNPs enable visualization of low-level mosaicism, absence of heterozygosity (AOH), copy number changes, and genomic contamination identification for research use.
With more than 2.6 million copy number markers, the assay covers all OMIM™ and RefSeq genes.
Our proprietary manufacturing technology ensures high reproducibility between batches with no risk of probe dropout inherent in bead-based manufacturing techniques.
The assay includes arrays, reagents, and easy-to-use data analysis software for a cost-effective and streamlined analysis of pluripotent stem cell lines.
주요 특징
- Broadest coverage and highest performance for detecting chromosomal abnormalities
- Karyotyping and genotyping (sample ID) with one assay
99% sensitivity; reliably detects 25–50 kb copy number changes
- Simple analysis; no cytogenetics expertise necessary
- Includes arrays, reagents, and free downloadable software
- Results in approximately 2.5 days
성능 비교
| 구분 | KaryoStat Assay | KaryoStat HD Assay |
|---|---|---|
| Gains | >2 Mb | >25–50 kb |
| Losses | >1 Mb | >25–50 kb |
| Absence of heterozygosity | >5 Mb | >1 Mb |
| SNP | Yes | Yes |
| Coverage | Low | Highest |
| Instrument | GeneChip Scanner 3000 only | GeneChip Scanner 3000 only |
| Analysis software | Chromosomal Analysis Suite | Chromosomal Analysis Suite |
사양
| 항목 | 내용 |
|---|---|
| 유형 | HD Assay |
| 어레이 수 | 24 arrays |
| 형식 | GeneChip Probe Array |
| 종 | Human |
| 용도(장비) | GeneChip Scanner 3000 |
| 포함 | Arrays, Reagents, Data Analysis Software |
| 제품 라인 | KaryoStat™ HD |
| 수량 | 24 assays |
| 배송 조건 | Approved for shipment at Room Temperature or on Wet or Dry Ice |
| Unit Size | Each |
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