
Thermo Fisher Scientific Cytokeratin 8 (KRT8) Monoclonal Antibody (H1, TS1)
인간 Cytokeratin 8 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC, Flow cytometry에 사용 가능. 단백질 구조 유지와 세포 분화 연구에 적합. 단백질 A/G 정제, PBS 용액 형태, 방부제 없음.
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- 3856-MSM5-P1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | H1, TS1 |
| Immunogen | Cytoskeleton preparation containing cytokeratin 8 (H1). Keratin preparation from a human carcinoma (TS1). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratin 8 is a member of the type II keratin family located on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate filaments in the cytoplasm of epithelial cells. Cytokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein contributes to maintaining cellular structural integrity and functions in signal transduction and cellular differentiation. Mutations in this gene are associated with cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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