Thermo Fisher Scientific Cytokeratin 8 (KRT8) Monoclonal Antibody (TS1)
인간 세포에서 Cytokeratin 8(KRT8)을 검출하는 Mouse IgG1 단일클론 항체. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합. 단백질 A/G로 정제된 액상 형태로, 4°C에서 보관. Rat 및 Ferret과 반응하지 않음.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC-PFA) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TS1 |
| Immunogen | Keratin preparation from a human carcinoma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Rat or Ferret.
Target Information
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.
Cytokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells.
This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation.
Mutations in this gene cause cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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