Thermo Fisher Scientific P glycoprotein Recombinant Rabbit Monoclonal Antibody (ARC0470)
P-glycoprotein을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA에 적합합니다. Human, Mouse, Rat 시료에 반응하며, HEK293 세포에서 발현되었습니다. 0.8 mg/mL 농도의 액상 형태로, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| ELISA | 1 µg/mL | View publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0470 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 393–710 of human P Glycoprotein (P08183) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849160 |
Product Specific Information
Immunogen sequence:
EFRNVHFSYP SRKEVKILKG LNLKVQSGQT VALVGNSGCG KSTTVQLMQR LYDPTEGMVS VDGQDIRTIN VRFLREIIGV VSQEPVLFAT TIAENIRYGR ENVTMDEIEK AVKEANAYDF IMKLPHKFDT LVGERGAQLS GGQKQRIAIA RALVRNPKIL LLDEATSALD TESEAVVQVA LDKARKGRTT IVIAHRLSTV RNADVIAGFD DGVIVEKGNH DELMKEKGIY FKLVTMQTAG NEVELENAAD ESKSEIDALE MSSNDSRSSL IRKRSTRRSV RGSQAQDRKL STKEALDESI PPVSFWRIMK LNLTEWPY
Target Information
The membrane-associated protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily, responsible for transporting various molecules across cellular membranes.
Members of the MDR/TAP subfamily, including this protein, are involved in multidrug resistance.
It functions as an ATP-dependent drug efflux pump with broad substrate specificity, contributing to decreased drug accumulation and resistance to anticancer drugs.
Additionally, it serves as a transporter in the blood-brain barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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