Thermo Fisher Scientific RALBP1 Monoclonal Antibody (OTI6G10), TrueMAB
RALBP1 단백질을 인식하는 Mouse Monoclonal Antibody로 Western blot, IHC, ICC, Flow cytometry, IP에 사용 가능. Human 시료 반응성. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G10 |
| Immunogen | Full length human recombinant RALBP1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
RALBP1 specifically activates hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. It mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX), functioning as a major ATP-dependent transporter of glutathione conjugates and xenobiotics in erythrocytes.
It also serves as a scaffold protein linking endocytotic complex proteins during interphase and interacts with CDC2 to regulate endocytosis. One of its substrates is EPN1/Epsin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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