Thermo Fisher Scientific Phospho-MEK3/MEK6 (Ser189, Ser207) Recombinant Rabbit Monoclonal Antibody (MKK3S189MKK6S207-D3), FITC
인간 및 마우스에서 반응하는 재조합 래빗 모노클로날 항체로, MEK3/MEK6의 인산화 상태(Ser189, Ser207)를 인식합니다. FITC 형광 표지로 유세포 분석에 적합하며, HEK293 발현 시스템 기반으로 정제된 고품질 항체입니다. 연구용으로만 사용됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MKK3S189MKK6S207-D3 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser189 of human phospho MKK3 and Ser207 of human phospho MKK6 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897251 |
Additional Formats
- Unconjugated (Cat. MA5-37054)
- APC (Cat. MA5-37057)
- PE (Cat. MA5-37055)
- Custom conjugation available upon request
Target Information
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein kinase kinase. MAP kinases act as integration points for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. It plays an essential role in p38 MAP kinase-mediated signal transduction, involved in processes such as stress-induced cell cycle arrest, transcription activation, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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