
Thermo Fisher Scientific PTP alpha Polyclonal Antibody, Biotin
PTP alpha 단백질을 인식하는 Biotin 결합 폴리클로날 항체로, Western blot, IHC, ELISA, IP에 적합합니다. Rabbit IgG 기반으로 높은 특이성과 재현성을 제공합니다. 인산화 조절 연구 및 신호전달 기전 분석에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 650–700 of human Receptor-type tyrosine-protein phosphatase Alpha (PTPRA, UniProt ID: P18433-5) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Phosphorylation of receptors by protein kinases can be reversed by protein phosphatases. These enzymes enable cells to switch between phosphorylated and dephosphorylated states in response to environmental stimuli. Proper regulation of kinase and phosphatase activity is essential for controlled cell growth and signaling. Dysregulation may lead to cancer or developmental disorders. Protein phosphatases influence multiple substrates and signaling pathways, playing a key role in coordinating cellular responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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