Thermo Fisher Scientific SLITRK1 Polyclonal Antibody
SLITRK1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunohistochemistry에 적합. 인간, 생쥐, 랫트 반응성. 동결건조 형태로 제공되며 장기 보관 시 -20°C에서 안정적 유지.
- 카탈로그번호
- OSS00383W-100UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 210–260 of human SLITRK1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: SLITRK1.
Target Information
SLIT and NTRK-like family 1 (Slitrk1) belongs to a protein family of six homologous transmembrane proteins (Slitrk1–6) sharing two conserved leucine-rich repeat domains in the extracellular region and significant homology to Slit, a secreted axonal growth-regulating protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains.
Expression of Slitrk proteins is largely restricted to neural and brain tumor tissues but varies among family members. Slitrk1 is predominantly expressed in mature neurons. Overexpression of Slitrk1 induces unipolar neurite formation, whereas other Slitrk proteins inhibit neurite outgrowth, suggesting roles in neurite development.
Variants of Slitrk1 have been associated with Tourette’s Syndrome, though their contribution appears minor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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