
Thermo Fisher Scientific SLITRK1 Polyclonal Antibody
SLITRK1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체. Western blot 및 IHC에 적합하며 인간, 생쥐, 랫드 반응성. 합성 펩타이드(aa 410-460)로 면역화. 연구용으로만 사용 가능.
- 카탈로그번호
- OSS00382W-100UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- Publications: View 1 publication
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
- Publications: View 1 publication
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 410–460 of human SLITRK1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: SLITRK1
Target Information
SLIT and NTRK-like family 1 (Slitrk1) belongs to a protein family of six homologous transmembrane proteins (Slitrk1–6) that share two conserved leucine-rich repeat domains in the extracellular region and show homology to Slit (axon growth-controlling protein) and Trk neurotrophin receptors in their intracellular domains.
Expression of Slitrk proteins is restricted to neural and brain tumor tissues but varies within the family. Slitrk1 is mainly expressed in mature neurons. Overexpression of Slitrk1 induces unipolar neurites, while other Slitrk proteins inhibit neurite outgrowth, suggesting involvement in neurite outgrowth control.
Variants of Slitrk1 have been suggested to be associated with Tourette’s Syndrome, though likely with minor relevance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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