Thermo Fisher Scientific OTUB1 Polyclonal Antibody
OTUB1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. Mouse와 Rat에 반응하며 Human 등 다양한 종에서 예측 반응성을 보입니다. 항원 친화 정제 방식으로 높은 특이도와 재현성을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of mouse OTUB1 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736282 |
Product Specific Information
- Positive Control: Mouse brain, Rat brain
- Predicted Reactivity: Human (100%), Dog (100%), Pig (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The OTUB1 protein belongs to the OTU superfamily of predicted cysteine proteases. It functions as a highly specific ubiquitin iso-peptidase, cleaving ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. OTUB1 interacts with other ubiquitin proteases and E3 ubiquitin ligases that regulate cytokine gene transcription in the immune system. It may play a role in specific ubiquitin-dependent pathways by editing polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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