Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI6B11), TrueMAB
인간 LIPG 단백질을 인식하는 마우스 단클론 항체로, WB, IHC, ICC, Flow, IP 등 다양한 응용 가능. 무보존제, 동결건조 형태로 제공되며, 재조합 단백질을 면역원으로 사용. 연구용으로 HDL 대사 및 지질 관련 연구에 적합.
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Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI6B11), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6B11 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions locally to modulate lipoprotein metabolism.
Overexpression of LIPG reduces HDL cholesterol levels, while deficiency elevates HDL levels. LIPG exhibits phospholipase activity and plays a role in lipoprotein metabolism and vascular biology.
It is a carboxyl esterase that hydrolyzes high-density lipoproteins, emulsifies triglycerides, and is essential for efficient digestion of dietary fats. LIPG can bind to heparin and is characterized by a lid region conferring substrate specificity typical of TG lipase family enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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