Thermo Fisher Scientific AS160 Polyclonal Antibody
AS160 (TBC1D4) 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품이며, 4°C에서 보관. 인슐린 유도 GLUT4 이동 및 당대사 연구에 적합.
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Thermo Fisher Scientific AS160 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200–250 of human Akt Substrate of 160 kDa (AS160, UniProt ID: O60343-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
AS160 (TBC1D4) is a GTPase-activating protein for RAB2A, RAB8A, RAB10, and RAB14.
Isoform 2 promotes insulin-induced translocation of glucose transporter SLC2A4/GLUT4 to the plasma membrane, enhancing glucose uptake.
Mutations in this gene are associated with Diabetes mellitus, non-insulin-dependent, type 5 (NIDDM5).
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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