Thermo Fisher Scientific AS160 Polyclonal Antibody
AS160 단백질을 표적하는 Rabbit Polyclonal Antibody로 다양한 응용(WB, IHC, IP)에 적합. 액상 형태로 1 mg/mL 농도, 4°C 보관 및 Wet ice 배송. 인슐린 유도 GLUT4 이동 연구 및 당뇨 관련 단백질 분석에 활용 가능.
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Thermo Fisher Scientific AS160 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 and 250 of human Akt Substrate of 160 kDa (AS160) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
AS160 (TBC1D4) is a GTPase-activating protein for RAB2A, RAB8A, RAB10, and RAB14.
Isoform 2 promotes insulin-induced translocation of glucose transporter SLC2A4/GLUT4 to the plasma membrane, increasing glucose uptake.
Mutations in this gene are associated with Diabetes mellitus, non-insulin-dependent, type 5 (NIDDM5).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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