Thermo Fisher Scientific REST/NRSF Polyclonal Antibody
REST/NRSF 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ELISA, IP 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며, REST 관련 신경 유전자 연구에 유용.
- 카탈로그번호
- REST-101AP
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1000–1097 of human REST protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
REST (RE1-Silencing Transcription Factor, also known as NRSF) is a transcriptional repressor that binds to the neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. It restricts neuronal gene expression by associating with corepressors mSin3 and CoREST, recruiting histone deacetylase to REST-regulated promoters. REST mediates repression by recruiting the BHC complex at RE1/NRSE sites, which deacetylates and demethylates histones, acting as a chromatin modifier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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