Thermo Fisher Scientific SUFU Polyclonal Antibody
Thermo Fisher Scientific의 SUFU Polyclonal Antibody는 인간과 마우스에 반응하며, Hedgehog 신호 경로 연구에 적합합니다. Western blot과 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제된 고품질 항체입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human Suppressor of Fused |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10999801 |
Product Specific Information
This antibody is predicted to react with rat, chicken, and dog based on sequence homology.
Target Information
The Hedgehog signaling pathway plays an important role in early human development. It regulates pattern formation and cellular proliferation during development. The SUFU gene encodes a negative regulator of this pathway, and defects in SUFU are associated with medulloblastoma. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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