Thermo Fisher Scientific Nkx6.1 Polyclonal Antibody
Rabbit polyclonal antibody against human Nkx6.1, validated for Western blot. Reacts with human, mouse, and rat samples. Supplied as liquid form, unconjugated, 1 mg/mL concentration. Ideal for research on pancreatic beta cell and CNS development.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Nkx6.1 (UniProt ID: P78426-1, antigen range: 221–245) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692039 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
NKX6.1 is a bi-functional transcription factor involved in both the central nervous system and pancreas. It regulates gene expression and repression to ensure proper formation of motoneurons, oligodendrocytes, and insulin-secreting beta cells. NKX6.1 interacts with Pax6 and Pdx-1 near the homeobox DNA-binding domain. Its role in beta cell and CNS development makes it a key target for diabetes and neurological disease research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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