Thermo Fisher Scientific LL37 Polyclonal Antibody
LL37에 특이적인 Rabbit Polyclonal Antibody로, Western Blot과 IHC에 사용 가능. Reptile 반응성 확인됨. 합성 Cathelicidin 펩타이드로 면역화됨. 항균 및 면역 조절 연구용으로 적합. 연구용(Reasearch Use Only) 제품.
- 카탈로그번호
- OSC00131W-100UL
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Reptile |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from Bungarus fasciatus Cathelicidin antimicrobial peptide (CAP-18, hCAP-18, antibacterial protein LL-37, CAMP, CRAMP) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Cathelicidin antimicrobial peptide.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells.
These molecules are essential for defense against invasive bacterial infection in skin.
Besides direct antimicrobial function, Cathelicidins mediate innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, neutrophil chemotaxis, and mast cell recruitment.
Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs for infection treatment or immune modulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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