Thermo Fisher Scientific ACE Recombinant Rabbit Monoclonal Antibody (ARC0577)
ACE 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ELISA, IP 분석에 적합합니다. HEK293 세포에서 발현되었으며, 고순도의 Affinity Chromatography 정제 항체입니다. 혈압 조절 관련 연구 등 ACE1 단백질 연구용으로 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 400–600 µg extracts |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0577 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1200–1306 of human ACE1 (P12821) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.18 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849004 |
Product Specific Information
Immunogen sequence:
YFKPLLDWLR TENELHGEKL GWPQYNWTPN SARSEGPLPD SGRVSFLGLD LDAQQARVGQ WLLLFLGIAL LVATLGLSQR LFSIRHRSLH RHSHGPQFGS EVELRHS
Target Information
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide, angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with circulating enzyme levels or cardiovascular pathophysiologies. Two abundant alternatively spliced variants encode the somatic and testicular isozymes, both active. Additional variants have been identified, though their full-length sequences remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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