Thermo Fisher Scientific RelB Monoclonal Antibody (17.3)
RelB 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC, Flow cytometry, IP 등 다양한 응용에 적합. Human, Mouse, Rhesus monkey 반응성. Recombinant RelB C-terminal 항원 유래, Protein A 정제, 0.5 mg/mL 농도. 연구용 전용.
- 카탈로그번호
- 437500
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific RelB Monoclonal Antibody (Clone 17.3)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rhesus monkey |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 17.3 |
| Immunogen | Recombinant protein derived from C-terminal region of human RelB protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2532220 |
Target Information
The NFκB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNA-binding subunit is functionally related to c-Rel p75 and RelB p68. The p50 subunit was initially believed to be a unique protein derived from the amino terminus of a precursor designated p105. A second protein, p52 (previously referred to as p49), can act as an alternative NFκB subunit. RelB does not bind with high affinity to NFκB sites, but heterodimers between RelB and p50 bind with affinity comparable to that of p50 NFκB homodimers. RelB/p50 heterodimers, unlike NFκB heterodimers, transactivate transcription of promoters containing κB binding sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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