Thermo Fisher Scientific CXCR1 Polyclonal Antibody
CXCR1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 고농도(1.97 mg/mL) 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. IL-8 수용체 연구 및 세포 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 272–350 of Human CXCR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.97 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2544660 |
Product Specific Information
- Recommended positive controls: HepG2, mouse leukocyte treated with CFA
- Predicted reactivity: Chimpanzee (100%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8), binding IL8 with high affinity and transducing signals via a G-protein–activated second messenger system. Knockout studies in mice suggest that CXCR1 inhibits embryonic oligodendrocyte precursor migration in the developing spinal cord. The IL8RB gene, encoding another high-affinity IL8 receptor, and IL8RBP, a pseudogene of IL8RB, form a gene cluster on chromosome 2q33–q36.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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