Thermo Fisher Scientific COPG Polyclonal Antibody
Rabbit polyclonal antibody against human COPG for use in WB, IHC, and ICC. High specificity and sensitivity with antigen affinity purification. Supplied in liquid form with PBS buffer and glycerol. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human COPG. Recombinant protein control fragment (Product #RP-104681) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665284 |
Product Specific Information
Immunogen sequence:
MLPSILVLLKR CVMDDDNEVR DRATFYLNVL EQKQKALNAG YILNGLTVSI PGLERALQQY TLEPSEKPFD LKSVPL
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, mediating biosynthetic protein transport from the ER via the Golgi to the trans-Golgi network. The coatomer complex is essential for Golgi-to-ER retrograde transport of dilysine-tagged proteins and is recruited by membranes associated with ADP-ribosylation factors (ARFs), small GTP-binding proteins. It also influences Golgi structural integrity, LDL receptor processing, and lipid homeostasis by regulating perilipin family members (PLIN2, PLIN3) and promoting adipocyte triglyceride lipase (PNPLA2) association with lipid droplets to mediate lipolysis.
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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