Thermo Fisher Scientific Cullin 3 Polyclonal Antibody
Human Cullin 3 단백질을 인식하는 goat polyclonal antibody로, Western blot 및 Peptide ELISA에 적합합니다. 비결합형 액상 형태이며, 고순도 정제 및 안정적 저장 조건을 제공합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5142413
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Publications
- Reference data not provided
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence C-AQVTGSNTRKHILQ (aa 580–593) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933061 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 1:2,000.
Target Information
Cullin 3 is a member of the human cullin gene family (CUL1, CUL2, CUL3, CUL4a, CUL4b, and CUL5), homologous to the S. cerevisiae cdc53 gene.
CUL1 forms a complex with human p19 skp1 and F-box protein p45 skp2. Together with cdc53 (known as Cul A), they constitute a ubiquitin ligase complex that regulates proteolysis of G1 cell cycle regulatory proteins.
In contrast, CUL2 does not associate with p19 skp1 and p45 skp2 but forms a complex with the inactive transcriptional elongation complex SIII, composed of Elongin C, Elongin B, and VHL. The function of this association remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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