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Thermo Fisher Scientific SCNN1D Polyclonal Antibody
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Human SCNN1D 단백질을 인식하는 Goat Polyclonal 항체로, IHC(P)에서 2.5 µg/mL 농도로 검증됨. 액상 형태로 0.5 mg/mL 농도이며, TBS(pH 7.3, 0.5% BSA) 용액에 보관. -20°C에서 보관하며 동결-해동 반복은 피해야 함.
- 카탈로그번호
- PA5142418
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오전 06:06
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Thermo Fisher Scientific PA5142418 SCNN1D Polyclonal Antibody 100 ug pk판매 단위 pk ·
재고 확인 필요
681,400원VAT 포함 749,540원
Thermo Fisher Scientific · Thermo Fisher Scientific SCNN1D Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-AGPQPLETLDT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933066 |
Product Specific Information
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000
- Preliminary analysis showed no signal in Western Blot.
Target Information
SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes:
- Type II receptors that bind ligand and recruit type I receptors to transduce the signal.
- SNX6 strongly interacts with ActRIIB and moderately with wild type and kinase-defective mutants of TbetaRII.
- Among type I receptors, SNX6 interacts only with inactivated TbetaRI.
- SNXs 1-4 also interact with the TGF-beta receptor family, showing different receptor preferences.
- SNX6 behaves similarly to other SNX proteins in interactions with receptor tyrosine kinases.
- Strong heteromeric interactions among SNX1, -2, -4, and -6 suggest formation of oligomeric complexes in vivo.
These findings provide evidence for the association of the SNX family with receptor serine-threonine kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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