Thermo Fisher Scientific SCNN1D Polyclonal Antibody
상품 옵션 정보 | |||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA5142418 | - | Thermo Fisher Scientific PA5142418 SCNN1D Polyclonal Antibody 100 ug pk | 재고문의 | pk | 697,000원 | - | 766,700원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Immunohistochemistry (Paraffin) (IHC (P))
2.5 µg/mL
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-AGPQPLETLDT. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
SCNN1D,
uniProtId:
P51172-3,
ncbiNodeId:
9606,
antigenRange:
792-802,
antigenLength:
802,
antigenImageFileName:
PA5-142418_SCNN1D_P51172-3_Goat.svg,
antigenImageFileNamePDP:
PA5-142418_SCNN1D_P51172-3_Goat_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2933066
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Preliminary analysis showed no signal in Western Blot.
Target Information
SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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