Thermo Fisher Scientific STEAP4 Polyclonal Antibody
Human STEAP4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. Affinity chromatography로 정제된 액상 형태이며 PBS+50% glycerol buffer에 보관. 세포 내 STEAP4 발현 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human STEAP4 (Accession Q687X5), corresponding to amino acid residues L422–H459 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900605 |
Product Specific Information
Antibody detects endogenous levels of total STEAP4.
Target Information
The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to STEAP2 and STEAP3, STEAP4 promotes both iron and copper reduction. It is highly expressed in placenta, lung, heart, and prostate tissues, and is overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting a role in cell proliferation and prostate cancer progression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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