Thermo Fisher Scientific STEAP3 Polyclonal Antibody
STEAP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫드 반응성. 액상 형태, 1 mg/mL 농도, 친화 크로마토그래피로 정제됨. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human STEAP3 (Accession Q658P3), corresponding to amino acid residues D16–R66 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900603 |
Product Specific Information
Antibody detects endogenous levels of total STEAP3.
Target Information
The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to STEAP2 and STEAP4, STEAP3 promotes both iron and copper reduction. It is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction, and mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 functions as an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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