Thermo Fisher Scientific H3K14me1me2me3 Polyclonal Antibody
H3K14me1me2me3 폴리클로날 항체로, 메틸화된 Histone H3 Lys14를 특이적으로 인식합니다. Western blot 및 ICC/IF에 사용 가능하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. -20°C에서 보관하며, 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic methylated peptide derived from human Mono-Di-Tri-Histone H3 around the methylation site of Lys14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815849 |
Product Specific Information
This antibody detects endogenous levels of Mono-Di-Tri-Histone H3 only when methylated at Lys14.
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with four core histone proteins, it binds to DNA to form the nucleosome structure. Histones play a crucial role in transcription regulation, DNA repair, replication, and chromosomal stability.
Post-translational modifications of histones, such as methylation or acetylation of lysine and arginine residues, and phosphorylation of serine or threonine residues, influence chromatin structure and gene expression.
The N-terminal tail of histone H3 extends from the nucleosome core and undergoes multiple types of modifications that regulate cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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