Thermo Fisher Scientific Ku70 Polyclonal Antibody
Ku70 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot에 적합하며 인간 시료에 반응. 합성 펩타이드 면역원으로 제작, 비결합형 액상 형태. 연구용으로 DNA 손상 복구 관련 연구에 유용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (YKTEGDEEAEEEQ) corresponding to the N-terminus amino acids of XRCC6 (aa 8–21) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10976968 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 1:2,000.
Target Information
XRCC6 (Ku70) forms a nuclear complex with a subunit of approximately 80 kDa. This complex acts as a single-stranded DNA-dependent, ATP-dependent helicase involved in the repair of nonhomologous DNA ends, such as those required for double-strand break repair, transposition, and V(D)J recombination. Elevated levels of autoantibodies to p70 and p80 have been observed in some patients with systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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