Thermo Fisher Scientific INTS1 Polyclonal Antibody
Rabbit polyclonal antibody against human INTS1 for ICC/IF applications. Recognizes INTS1 subunit of Integrator complex involved in RNA polymerase II function. Antigen affinity purified, supplied in PBS with glycerol and sodium azide. For research use o...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human INTS1. Recombinant protein control fragment (Product #RP-106434) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664028 |
Product Specific Information
Immunogen sequence:
KLDGLIHRFIT LLADTSDSRA LENRGADASM ACRKLAVAHP LLLLRHLPMI AALLHGRTHL NFQEFRQQNH LSCF
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 25%
Target Information
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of the RNA polymerase II large subunit and mediates 3′ end processing of small nuclear RNAs U1 and U2. RNA polymerase II (Pol II) is an enzyme composed of twelve subunits responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, allowing transcription to begin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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