Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1 Chimeric Recombinant Human Monoclonal Antibody (H6)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1:10,000-1:50,000

-

Neutralization (Neu)

1:50-1:10,000

View 2 publications 2 publications

Lateral Flow (LF)

1:500-1:5,000

-

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Virus

Published species

Human, Virus

Host/Isotype

Human / IgG1, Fc

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

H6

Immunogen

Recombinant Human Novel Coronavirus Spike glycoprotein (S) (16-685aa)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_2866551

Product Specific Information

Recombinant anti-SARS-CoV-2 spike Mouse ScFv is expressed from 293 cells(HEK293) with a human IgG1 Fc tag on C-terminal.

Target Information

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain (Spike Protein). The Spike protein is the main surface antigen of the coronavirus. The glycosylated Spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. CoV diversity is reflected in the variable Spike proteins (S proteins), which have evolved into forms differing in their receptor interactions and their response to various environmental triggers of virus-cell membrane fusion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.