Thermo Fisher Scientific CaV1.2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1.0-3.0 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide sequence (RARGRPSEEELQD) corresponding to the C-terminus amino acids of CACNA1C (aa 2201-2214). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CaV1.2,uniProtId:Q13936-1,ncbiNodeId:9606,antigenRange:2201-2214,antigenLength:2221,antigenImageFileName:PA5-18991_CaV1.2_Q13936-1_Goat.svg,antigenImageFileNamePDP:PA5-18991_CaV1.2_Q13936-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_10980194

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

Target Information

CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.