Thermo Fisher Scientific CaV1.2 Polyclonal Antibody
CaV1.2 단백질을 인식하는 Thermo Fisher Scientific의 goat polyclonal 항체. 인간 시료 반응성, WB 검증 완료. 합성 펩타이드 기반 면역원 사용. 고순도 액상 형태로 공급되며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0–3.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RARGRPSEEELQD) corresponding to the C-terminus amino acids of CACNA1C (aa 2201–2214) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980194 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization.
The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell.
The calcium channel complex includes alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
Multiple isoforms exist due to alternative splicing or different gene encoding.
The CACNA1C protein binds to and is inhibited by dihydropyridine.
Alternative splicing results in many transcript variants encoding different proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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