Thermo Fisher Scientific STX17 Polyclonal Antibody
STX17 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P)에서 사용 가능. Human, Mouse, Rat에 반응하며, Affinity chromatography로 정제됨. PBS buffer(50% glycerol) 보존, -20°C 보관. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human STX17 (Accession P56962), corresponding to amino acid residues G257–S302. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2854110 |
Product Specific Information
Antibody detects endogenous levels of total Syntaxin 17.
Target Information
SNAREs (soluble N-ethylmaleimide-sensitive factor-attachment protein receptors) are essential proteins for the fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.
STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. It may also play a role in the early secretory pathway, maintaining the architecture of the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) and Golgi, and regulating transport between these organelles. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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