Thermo Fisher Scientific RCC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

His-tagged recombinant Xenopus RCC1 protein purified from E. coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2179591

Product Specific Information

PA1-5868 detects RanGEF in human and xenopus samples.

PA1-5868 has been successfully used in immunofluorescence, immunoprecipitation, immunohistochistry and Western blot procedures.

The PA1-5868 immunogen is His-tagged recombinant Xenopus RCC1 protein purified from E. coli.

Target Information

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.