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Thermo Fisher Scientific Topoisomerase II alpha Recombinant Rabbit Monoclonal Antibody (TOP2A, 6570R)
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Thermo Fisher Scientific Topoisomerase II alpha Recombinant Rabbit Monoclonal Antibody (TOP2A, 6570R)

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Recombinant rabbit monoclonal antibody targeting human Topoisomerase II alpha (TOP2A). Validated for WB and IHC applications. High specificity and sensitivity for cell cycle phase detection. Supplied as unconjugated liquid form, 1 mg/mL concentration, ...

카탈로그번호
7153-RBM5-P1ABX
판매단위
pk
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마지막 업데이트 2025. 08. 03. 오후 12:10
Thermo Fisher Scientific 7153-RBM5-P1ABX Topoisomerase II alpha Recombinant Rabbit Monoclonal Antibody (TOP2A, 6570R) 100 ug pk판매 단위 pk ·
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829,000원VAT 포함 911,900원

Thermo Fisher Scientific · Thermo Fisher Scientific Topoisomerase II alpha Recombinant Rabbit Monoclonal Antibody (TOP2A, 6570R)

Applications

Western Blot (WB)

  • Assay-dependent

Immunohistochemistry (Paraffin) (IHC (P))

  • 1–2 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone TOP2A, 6570R
Immunogen Recombinant human Topoisomerase II alpha fragment (aa1352–1493)
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Protein A/G
Storage Buffer PBS, pH 7.4
Contains No preservative
Storage Conditions -20°C or -80°C if preferred
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • For immunohistochemistry (PFA-fixed): incubate antibody for 30 minutes at room temperature.
  • Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

Topoisomerase II alpha (Topo IIα) plays an essential role in DNA synthesis, transcription, and chromosomal segregation during mitosis.
It serves as a sensitive and specific marker for late S-, G2-, and M-phases in transformed and developmentally regulated normal cells.
Topo IIα is also associated with tumor cell drug resistance.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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