Thermo Fisher Scientific Caspase 1 Polyclonal Antibody
Caspase 1 단백질 검출용 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. Western blot에 1:500~1:1,000 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관, 연구용 전용 시약입니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 200–250 of Human CASP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.2) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2803694 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
Caspases are a family of cysteine proteases divided into apoptotic and inflammatory subfamilies. Unlike apoptotic caspases, inflammatory caspases are generally not involved in cell death but play roles in immune responses to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12, which activate proinflammatory cytokines such as IL-1β and IL-18.
Caspase-1 was initially identified as an IL-1β-converting enzyme and later found to be a mammalian homolog of the C. elegans cell death gene ced-3, whose overexpression can induce apoptosis in fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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