Thermo Fisher Scientific Dysferlin Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Dysferlin. Recombinant protein control fragment (Product #RP-90255). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Dysferlin,uniProtId:O75923-1,ncbiNodeId:9606,antigenRange:645-783,antigenLength:2080,antigenImageFileName:PA5-54541_Dysferlin_O75923-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54541_Dysferlin_O75923-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.08 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640856

Product Specific Information

Immunogen sequence: CHYYYLPWGN VKPVVVLSSY WEDISHRIET QNQLLGIADR LEAGLEQVHL ALKAQCSTED VDSLVAQLTD ELIAGCSQPL GDIHETPSAT HLDQYLYQLR THHLSQITEA ALALKLGHSE LPAALEQAED WLLRLRALA

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.

Target Information

Dysferlin is the protein product of the 2p13 gene that is defective in patients with Limb-Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM). Dysferlin is normally localized to the muscle plasma membrane. In patients with LGMD2B and MM, immunoreactivity to dysferlin is severely reduced or lost, depending on the type of mutation. This antibody is used for the characterization of LGMD2B and MM.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.