Thermo Fisher Scientific ATP5G1/2/3 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

The ATP5MC1 gene is one of three human paralogs that encode membrane subunit c of the mitochondrial ATP synthase, mapped to 17q21.32.
This gene encodes a subunit of mitochondrial ATP synthase, which catalyzes ATP synthesis utilizing an electrochemical proton gradient across the inner membrane during oxidative phosphorylation.
ATP synthase consists of two linked multi-subunit complexes: the soluble catalytic core (F1) and the membrane-spanning proton channel (Fo).
The catalytic portion includes five subunits (α, β, γ, δ, ε) with a 3α:3β:1 stoichiometry, while the proton channel contains nine subunits (a, b, c, d, e, f, g, F6, and 8).
Each of the three genes encoding subunit c has distinct mitochondrial import sequences but produces the same mature protein.
Alternatively spliced transcript variants encoding the same protein have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.