Thermo Fisher Scientific Prolactin Receptor Monoclonal Antibody (U5)
Thermo Fisher Scientific의 Prolactin Receptor Monoclonal Antibody (U5)는 rat, human, rabbit, horse, pig 등 다양한 조직에서 PRL 수용체를 검출합니다. Western blot, IHC, ICC, IP, FACS 등 다양한 응용에 적합하며, 단일클론 마우스 IgG1 항체로 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 15 publications |
| Immunohistochemistry (IHC) | - | View 11 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | View publications |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | View publications |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | View 6 publications |
| Flow Cytometry (Flow) | Assay-dependent | View publications |
| Immunoprecipitation (IP) | Assay-dependent | View 2 publications |
| Neutralization (Neu) | - | View 1 publication |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Horse, Human, Mouse, Pig, Rabbit, Rat |
| Published Species | Baboon, Bovine, Hamster, Human, Mouse, Non-human primate, Pig, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | U5 |
| Immunogen | Purified rat liver PRL receptor |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2171291 |
Product Specific Information
MA1-610 detects prolactin (PRL) receptor from rat, human, rabbit, horse, and pig tissues.
It has been successfully used in Western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunofluorescence, and FACS procedures.
By Western blot, this antibody detects ~40 kDa and ~100 kDa proteins representing short and long forms of the PRL receptor.
Immunohistochemical staining in rat Islets of Langerhans shows cytoplasmic vesicle staining.
After biotinylation, MA1-610 detects human lymphocyte PRL receptor by FACS.
It does not inhibit prolactin-receptor interaction.
Reconstitute with 100 µL PBS.
Target Information
Prolactin (PRL) is a pituitary hormone involved in milk production, salt and water regulation, growth, development, and reproduction.
PRL acts through a transmembrane PRL receptor initiating signal transduction.
The PRL receptor (PRLR), part of the cytokine receptor family, varies in size from ~40 to 100 kDa depending on tissue and species.
PRLR has three domains: an extracellular region with 5 cysteines containing the prolactin binding site, a single transmembrane domain, and a cytoplasmic region that regulates ligand binding and cellular function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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