Thermo Fisher Scientific IREB2 Monoclonal Antibody (1F3)
Thermo Fisher Scientific의 IREB2 Monoclonal Antibody (1F3)은 인간 IREB2 단백질을 인식하는 Mouse IgG2a 항체로, WB, ICC/IF, ELISA에 적합합니다. Affinity chromatography로 정제되었으며, PBS buffer에 보존되어 있습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- H00003658-M04
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- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F3 |
| Immunogen | IREB2 (AAH17880, 1 a.a. ~343 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MDAPKAGYAF EYLIETLNDS SHKKFFDVSK LGTKYDVLPY SIRVLLEAAV RNCDGFLMKK EDVMNILDWK TKQSNVEVPF FPARVLLQDF TGIPAMVDFA AMREAVKTLG GDPEKVHPAC PTDLTVDHSL QIDFSKCAIQ NAPNPGGGDL QKAGKLSPLK VQPKKLPCRG QTTCRGSCDS GELGRNSGTF SSQIENTPIL CPFHLQPVPE PETVLKNQEV EFGRNRERLQ FFKWSSRVFK NVAVIPPGTG MAHQINLEYL SRVVFEEKDL LFPDSVVGTD SHITMVNGLG ILGWGVGGIE TEAVMLGLPV SLTLPEVVGC ELTGSSNPFV TSIDVVLGIT KVS
Target Information
Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures and is regulated by iron-mediated proteolysis. Hypoxia plays a role in normal tissue physiology and several pathophysiological conditions, including cardiovascular diseases and tumor growth. Since iron and oxygen are closely related, IRP2 also functions during hypoxia (low oxygen).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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