Thermo Fisher Scientific MED14 Polyclonal Antibody
MED14 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트 시료에 반응합니다. Western Blot과 ELISA에 사용 가능하며, 고순도 Affinity Chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관하며 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 470–650 of human MED14 (NP_0042202) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.54 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804499 |
Product Specific Information
- Immunogen sequence: LDQATLDDME KSVNDDMKRI IPWIQQLKFW LGQQRCKQSI KHLPTISSET LQLSNYSTHP IGNLSKNKLF IKLTRLPQYY IVVEMLEVPN KPTQLSYKYY FMSVNAADRE DSPAMALLLQ QFKENIQDLV FRTKTGKQTR TNAKRKLSDD PCPVESKKTK RAGEMCAFNK VLAHFVAMCD T
- Positive Samples: HeLa, SW480, Jurkat, Mouse brain, Mouse pancreas
- Cellular Location: Nucleus
Target Information
The activation of gene transcription is a multistep process triggered by factors recognizing transcriptional enhancer sites in DNA. These factors cooperate with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.
The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is essential for efficient activation by SP1. It is also part of other multisubunit complexes such as thyroid hormone receptor-associated proteins (TRAPs) that interact with TR and facilitate TR function on DNA templates.
This protein contains a bipartite nuclear localization signal and escapes chromosome X-inactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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