Thermo Fisher Scientific MED14 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 470-650 of human MED14 (NP_0042202) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MED14,uniProtId:O60244-1,ncbiNodeId:9606,antigenRange:470-650,antigenLength:1454,antigenImageFileName:PA5-87913_MED14_O60244-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87913_MED14_O60244-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.54 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804499

Product Specific Information

Immunogen sequence: LDQATLDDME KSVNDDMKRI IPWIQQLKFW LGQQRCKQSI KHLPTISSET LQLSNYSTHP IGNLSKNKLF IKLTRLPQYY IVVEMLEVPN KPTQLSYKYY FMSVNAADRE DSPAMALLLQ QFKENIQDLV FRTKTGKQTR TNAKRKLSDD PCPVESKKTK RAGEMCAFNK VLAHFVAMCD T; Positive Samples: HeLa, SW480, Jurkat, Mouse brain, Mouse pancreas; Cellular Location: Nucleus

Target Information

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.