Thermo Fisher Scientific AQP0 Polyclonal Antibody
AQP0 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB 및 IHC에 적합합니다. 마우스, 랫트, 기니피그 반응성. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적입니다. 렌즈 섬유세포 연구에 유용합니다.
- 카탈로그번호
- OSA00180W-100UL
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Guinea pig, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 210–263 of mouse AQP0 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and guinea pig.
- Specificity: AQP0.
Target Information
AQP0 is the most abundant endogenous protein in the plasma membrane of lens fiber cells. It functions as a water pore and plays a role in fiber-fiber adhesion, crucial for fiber cell structure and organization.
AQP0 has an additional pore constriction unique among aquaporins, possibly responsible for pore gating.
The closed AQP0 pore holds three water molecules spaced too far apart to form hydrogen bonds.
The C-terminal domain undergoes extensive post-translational modifications, including truncations during lens aging, which may contribute to cataract formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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