Thermo Fisher Scientific UBXN2B Monoclonal Antibody (OTI1F9), TrueMAB
UBXN2B 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody입니다. Western blot과 IHC(P)에서 검증되었으며, 고순도의 Affinity chromatography 정제 제품입니다. 동결건조 형태로 제공되며, 재구성 및 결합 실험에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F9 |
| Immunogen | Full length human recombinant protein of human UBXN2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
UBXN2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 or p97 cofactor p37, is a 331 amino acid protein containing one UBX domain and one SEP domain.
UBXN2B is required for endoplasmic reticulum (ER) and Golgi biogenesis, maintenance during interphase, and reassembly at the end of mitosis.
Through its interaction with VCP, UBXN2B forms a complex with membrane fusion activity.
It acts as an adapter protein essential for Golgi and ER organization, with membrane fusion activity requiring USO1-GOLGA2 tethering and BET1L.
VCPIP1 is also required, though its deubiquitinating activity is not essential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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